Table 3.
Summary of the expression levels determined by DNA microarray analyses comparing H460 cells to cisplatin-resistant H460 cells (H460R), CSC H460 cells (H460C)
Gene | Accession number | Description | Fold change (H460R) | Fold change (H460C) | Fold change (H460CDif) |
---|---|---|---|---|---|
EGR1 | NM_001964 | Early growth response 1 | 38.08 | 12.78 | – |
JUN | NM_002228 | Proto-oncogene | 13.39 | 13.27 | – |
PTGS2/COX2 | NM_000963 | Prostaglandin-endoperoxide synthase 2/Cyclooxygenase 2 | 4.62 | 17.84 | – |
MALAT1 | NR_002819 | Metastasis-associated lung adenocarcinoma transcript 1 | 8.59 | 5.15 | – |
AKAP12 | NM_144497 | Kinase (PRKA) anchor protein 12 | 3.51 | 7.16 | – |
ADM | NM_001124 | Adrenomodullin | 5.13 | 5.6 | −4.8 |
CXCR4 | NM_001008540 | Chemokine (C-X-C motif) receptor 4 | – | 8.02 | −7.5 |
IL1B | NM_000576 | Interleukin 1, beta | – | 8.73 | −5.1 |
LOXL2 | NM_002318 | Lysyl oxidase-like 2 | – | 6.72 | −8.2 |
The right column compares CSC cells before and after culture under adherent conditions for 24 h (H460CDif).