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. 2014 Dec 31;11:211. doi: 10.1186/s12974-014-0211-6

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© Pepe et al.; licensee BioMed Central. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Time course of IL4-induced M2 gene expression in frontal cortex and striatum. Following the indicated time intervals after intracerebroventricular injection of saline (Veh) or IL4, the RNA extracted from the frontal cortex (Fr cortex) and striatum was analyzed by real time PCR to evaluate (A) Fizz1, (B) Arg1, and (C) Ym1 gene expression. Data sets for each gene were calculated using the 2^-ddCt method with respect to the mean value of the 8 h vehicle group. Bars represent mean values ± SEM. * P < 0.05 versus Veh; ** P < 0.01; *** P < 0.0005 versus Veh; ° P < 0.05 versus IL4 8 h; °° P < 0.05 versus IL4 16 h (n = 4 to 6); a P < 0.0005 versus striatum 8 h; b P < 0.05 versus striatum 8 h; bb P < 0.05 versus striatum 16 h.

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