Table 1.

Top significantly enriched ‘Biological Process’ GO terms among upregulated and downregulated genes during monocarpic senescence in wheat and in the 316 high-confidence GPC-A1- and 224 GPC-B2- regulated genes

	Accession	Ontology	Annotated	Significant	Expected	P
Upregulated	GO:0055114	Oxidation-reduction process	3168	171	87.5	2.60E-18
	GO:0055085	Transmembrane transport	1622	90	44.8	2.20E-10
	GO:0071577	Zinc ion transmembrane transport	20	8	0.55	3.10E-08
	GO:0034220	Ion transmembrane transport	369	31	10.19	4.90E-08
	GO:0006829	Zinc ion transport	24	8	0.66	1.60E-07
	GO:0043562	Cellular response to nitrogen levels	14	6	0.39	1.10E-06
	GO:0009064	Glutamine family amino acid metabolic process	65	11	1.8	1.50E-06
	GO:0006787	Porphyrin-containing compound catabolic process	76	11	2.1	7.40E-06
	GO:0033015	Tetrapyrrole catabolic process	76	11	2.1	7.40E-06
	GO:0051187	Cofactor catabolic process	76	11	2.1	7.40E-06
Downregulated	GO:0015979	Photosynthesis	502	123	11.06	<1e-30
	GO:0009765	Photosynthesis, light harvesting	76	47	1.67	<1e-30
	GO:0019684	Photosynthesis, light reaction	340	69	7.49	<1e-30
	GO:0006091	Generation of precursor metabolites and energy	774	78	17.06	1.70E-29
	GO:0033014	Tetrapyrrole biosynthetic process	183	30	4.03	9.60E-18
	GO:0015977	Carbon fixation	45	17	0.99	3.40E-17
	GO:0006779	Porphyrin-containing compound biosynthetic process	161	27	3.55	2.30E-16
	GO:0015995	Chlorophyll biosynthetic process	122	23	2.69	2.80E-15
	GO:0033013	Tetrapyrrole metabolic process	262	31	5.77	3.20E-14
	GO:0055114	Oxidation-reduction process	3168	134	69.81	5.50E-14
GPC1- regulated	GO:0005385	Zinc ion transmembrane transporter activity	29	13	0.14	2.00E-23
	GO:0046915	Transition metal ion transmembrane transmembrane activity	68	13	0.32	7.80E-18
	GO:0072509	Divalent inorganic cation transmembrane activity	95	13	0.44	7.80E-16
	GO:0046873	Metal ion transmembrane transporter activity	317	15	1.48	3.00E-11
	GO:0022890	Inorganic cation transmembrane transport activity	472	15	2.21	7.20E-09
	GO:0022891	Substrate-specific transmembrane transport	1016	20	4.76	6.60E-08
	GO:0015075	Ion transmembrane transporter activity	911	18	4.26	3.00E-07
	GO:0022892	Substrate-specific transporter activity	1132	20	5.3	3.70E-07
	GO:0008324	Cation transmembrane transporter activity	647	15	3.03	4.30E-07
	GO:0005215	Transporter activity	1989	26	9.31	1.90E-06
GPC2- regulated	GO:0009834	Secondary cell wall biogenesis	17	2	0.03	0.00041
	GO:0009832	Plant-type cell wall biogenesis	52	2	0.09	0.00382
	GO:0007017	Microtubule-based process	379	4	0.67	0.00446
	GO:0006812	Cation transport	948	6	1.67	0.00623
	GO:0071669	Plant-type cell wall organization or biogenesis	69	2	0.12	0.00664
	GO:0006811	Ion transport	1285	7	2.27	0.00701
	GO:0007029	Endoplasmic reticulum organization	5	1	0.01	0.00879
	GO:0015801	Aromatic amino acid transport	5	1	0.01	0.00879