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. Author manuscript; available in PMC: 2015 Jan 22.
Published in final edited form as: Pharmacol Res. 2014 May 17;85:45–54. doi: 10.1016/j.phrs.2014.05.004

Figure 7.

Figure 7

A. Representative images for F4/80 expression, an indicator for activated macrophage, at 200X and number of F4/80+ cells per mm2 (n=4) in the kidney of streptozotocin-induced diabetic mice with or without ABT702 treatment. Renal P-65NFB (B) and urinary MCP-1 excretion (C) in control, diabetic and ABT702 treated control and diabetic mice (n=7–8/group). Number of renal F4/80+ cells, renal P-65NFKB and urinary MCP-1 excretion level were significantly elevated in diabetic compared with control mice (*P <0.05 vs. control mice). ABT702 treatment significantly decreased these parameters in diabetic mice (#P <0.05 vs. diabetic mice, n=7–8/group).