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. Author manuscript; available in PMC: 2015 Mar 1.
Published in final edited form as: Arthritis Rheumatol. 2014 Mar;66(3):610–621. doi: 10.1002/art.38237

Figure 2. Arthritis-susceptible MHCII dependent anti-mC5a IgG induction.

Figure 2

(A–C) Collagen induced arthritis susceptible mouse strains expressing the human MHCII DR4 allele (hDR4, A) or murine H-2r (B) and H-2q (C) haplotypes were injected with the different C5a-4NPA variants (3 mice/group). Sera at d14 were screened for an IgG response crossreacting with murine wtC5a. Data show means with SD.