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. 2015 Jan 15;142(2):242–257. doi: 10.1242/dev.105445

Fig. 5.

Fig. 5.

Regulatory module responsible for neural crest EMT. Activity of Snai1/2, FoxD3, Twist and Zeb2 (Sip1) mediate changes in cell-cell interaction that allow for delamination and dispersion of neural crest cells (NCC). Repression of the epithelial cadherins Ncad, Ecad and Cad6b and activation of the type 2 cadherins Cad11 and Cad7 allow for changes in cell adhesion and EMT.