Table 1.
Clone ID | Event | Chrom | Fish | STS | Dup. contenta | Gene contenta | Avg. Log2 ratio | |||
PPA | PTR | GGO | PPY | |||||||
RP11-88L18 | Duplication | 5 | 5p15 | AFM105XG1 | Intra, ∼50 kb @ 99% | None | −0.25 | −0.10 | −1.13 | 0.65 |
RP11-64I02 | Duplication | 7 | 7p14 | SHGC-33366 | None | RFP-1 | 0.15 | 0.15 | 0.71 | −0.18 |
RP11-218N24 | Duplication | 8 | 8p22 | SHGC-11994 | None | CTSB, FDFT1, GATA4 | 0.67 | 0.51 | 0.08 | 0.32 |
RP11-209M09 | Duplication | 11 | 11p15 | SHGC-14668 | Intra, ∼50 kb @ 98% | RRM1 | 0.81 | 0.29 | −0.09 | 0.27 |
RP11-56J22 | Duplication | 11 | 11p15.1 | AFM210yb8 | None | None | −0.09 | −0.14 | −0.11 | 0.69 |
RP11-194H07 | Duplication | 15 | 15q14 | SHGC-24145 | Intra, ∼40 kb @ 99% | SLC12A6, NOLA3, KIAA0855 | 0.47 | 0.36 | −0.06 | 1.23 |
RP11-49M06 | Duplication | 16 | 16p13.2 | SHGC-11261 | None | PIG7, SNN, LOC51061 | 0.04 | 0.10 | 0.13 | 1.20 |
RP11-171I08 | Deletion | 11 | 11p11.12 | WI-636 | Intra, ∼30 kb @ 95% | None | −0.01 | −0.06 | −0.49 | −0.96 |
RP11-75H24 | Deletion | 11 | 11q12.3 | G29694 | Intra, ∼50 kb @ 95% | None | −0.61 | −0.64 | 0.00 | −0.46 |
Defined as within 100 kb proximal or distal of the BAC-linked STS according to the UCSC Genome Browser, August 2001 assembly.
Average Log2 ratios exceeding the +/−0.5 threshold are indicated in bold type.
Experimentally verified gains and losses among great ape species, with respect to the human genome, were mapped and characterized for local duplication and genic content. The species average Log2 ratios for each variant site are shown for all species examined. Duplication content is indicated with the type, approximate size, and percent similarity of the duplications involved.