Table 3.
Comparison of Biomarkers One Year After Delivery of the Participants With and Without a Hypertensive Disorder
| Control | Hypertensive disorder of pregnancy | p-Value | |
|---|---|---|---|
| Number of participants (n=71) | 40 | 31 | |
| Inflammatory biomarkers | |||
| TNF-α, pg/mL* | 4.0 (5.3) | 8.8 (13.2) | <0.01 |
| hsCRP, ng/mLa | 8.7 (3.4) | 12.3 (15.7) | 0.39 |
| hsCRP>3 ng/L, n (%) | 23 (59.0%) | 18 (58.1%) | 0.94 |
| IL-6, pg/mL | 8.1 (2.5) | 8.2 (2.4) | 0.94 |
| Lipids | |||
| Total cholesterol | 181.9 (29.1) | 183.9 (31.7) | 0.78 |
| Triglycerides | 92.9 (43.5) | 96.6 (54.4) | 0.76 |
| HDL cholesterol | 52.9 (9.2) | 54.5 (12.9) | 0.56 |
| LDL cholesterol | 110.5 (25.2) | 110.2 (28.6) | 0.96 |
| Glucose metabolism | |||
| HgbA1c | 5.4 (0.4) | 5.4 (0.4) | 0.37 |
| HOMA-IR | 2.0 (1.6) | 2.6 (1.9) | 0.21 |
Values are given as mean±standard deviation for continuous data; n (%) for categorical data. Significance testing using t-test and chi2 for continuous and categorical data respectively using control as the referent group.
a
Log transformed for normality; transformation reversed for presentation.
HDL, high-density lipoprotein; HgbA1c, hemoglobin A1c; HOMA-IR, homeostasis model assessment–estimated insulin resistance; hsCRP, c-reactive protein; IL-6, interleukin-6; LDL, low-density lipoprotein; TNF-α, tumor necrosis factor alpha.