Table 3.
Cytotoxicity of TQ-NLC as reflected by the IC50 value at various incubation times determined by using MTT assay.
| Cell line | IC50 value (μM) | ||
|---|---|---|---|
| 24 h | 48 h | 72 h | |
| Cancerous cell line | |||
| MDA-MB-231 | 6.50 ± 0.50a | 4.43 ± 0.12b | 4.47 ± 0.06b |
| MCF-7 | >50 | >50 | >50 |
| SiHa | 19.42 ± 0.33c | 10.42 ± 0.17d | 8.50 ± 0.14e |
| HeLa | 23.00 ± 0.14f | 18.17 ± 0.51g | 15.58 ± 0.17h |
| Normal cell line | |||
| 3T3-L1 | NP | NP | >50 |
| Vero | NP | NP | 32.00 ± 0.29i |
Values were the means of three replicate samples. The data were presented as mean ± SEM. a, b, c, d, e, f, g, h, and i were significantly different (P < 0.05).
NP = not performed.