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. 2014 Nov 7;26(1):26–35. doi: 10.1089/hum.2014.115

FIG. 2.

FIG. 2.

Anti-CD4 mAb enhanced biochemical correction with AAV2/9-CBhGAApA in GAA-KO mice. GAA-KO mice were treated with AAV2/9-CBhGAApA (+) anti-CD4 (3 times; n=6) or without (−) anti-CD4 (n=11) pretreatment, corresponding to groups G2 and G4, respectively. The untreated (G1) group was used for a negative control. At week 14 or 24 following injection, mice were euthanized for tissue analysis. (A) GAA activity. (B) Glycogen content. *p<0.05; **p<0.01; ***p<0.001.