Table.
Functional Parameter | Group | Time = 0 (baseline) | Time = 20 min (end of pre-ischemic perfusion) | Time = 170 min (120 min of reperfusion) |
---|---|---|---|---|
CPP (mmHg) | IR | 36 ± 2 | 36 ± 2 | 81 ± 8*** |
OIR | 40 ± 4 | 45 ± 5 | 93 ± 9*** | |
EDP (mmHg) | IR | 6 ± 1 | 6 ± 1 | 53 ± 8*** |
OIR | 5 ± 1 | 6 ± 2 | 42 ± 4*** | |
LVDP (mmHg) | IR | 61 ± 2 | 61 ± 2 | 18 ± 5*** |
OIR | 66 ± 3 | 67 ± 4 | 16 ± 2*** |
IR, untreated ischemia/reperfusion; OIR, oubain (100nM) pretreatment ischemia/reperfusion; CPP, coronary perfusion pressure; EDP, end diastolic pressure; LVDP, left ventricular developed pressure. Values are mean ±SEM from 9 independent experiments.
P<0.001 vs. respective baselines (value at time=0).