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. 2014 Nov 22;16:466. doi: 10.1186/s13058-014-0466-y

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© Toffoli et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fluorescent in situ hybridization analysis of the 17q25.3 chromosomal region in BRCA1 -mutated and non-mutated triple-negative breast cancer (TNBC). Samples were hybridized with a chromosome 17 centromeric probe (green) and the 17q25.3-specific BAC probe (RP11-1055B8) (red). Copy number gain in the 17q25.3 region is clearly visible in this representative mutated case.