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. 2014 Dec 16;16:495. doi: 10.1186/s13058-014-0495-6

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© Fan et al.; licensee BioMed Central. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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An identified cancer and corresponding plot of measured tumor volume as a function of mouse age. (a) A cancer (circled) in the thoracic gland from week ~10 to ~22. A tiny cancer found at week 10 developed into an invasive cancer at week 14, and the size of cancer increased dramatically after that. The displayed image field of view is 25 mm × 20 mm. (b) Plot of the tumor volume (black dots) calculated as a function of mouse age and fitted (red line) with the simple exponential tumor growth model.