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. 2015 Jan 22;11(1):e1004042. doi: 10.1371/journal.pcbi.1004042

Table 3. Experimentally validated gene-miRNA interactions with strong evidence from miRTarbase in ovarian cancer modules.

Module ID Gene miRNA Validation Method PubMed ID
2 EPB41L3 miR-223 Luciferase reporter assay, Western blot 21628394
2 MEF2C miR-223 Luciferase reporter assay 18278031
2 MEF2C miR-21 Immunofluorescence, In situ hybridization, Luciferase reporter assay 21170291
3 E2F1 miR-93 Luciferase reporter assay, Western blot 19486339
3 E2F1 miR-106b Luciferase reporter assay, Western blot 19486339
3 EZH2 miR-25 Luciferase reporter assay, qRT-PCR, Western blot 22399519
5 CREBZF miR-221 Reporter assay, Microarray 20018759
6 CCNE2 miR-26a Luciferase reporter assay, Western blot 19524505
13 CDC42 miR-29a Luciferase reporter assay, Western blot 19079265
14 BCL3 miR-125b Luciferase reporter assay 20658525
14 HK2 miR-125b Luciferase reporter assay, qRT-PCR 22593586
18 NASP miR-29a Luciferase reporter assay, Western blot 22080513
26 CCNA2 let-7b Immunoblot, Immunofluorescence, Luciferase reporter assay, qRT-PCR 18379589
27 TWIST1 miR-214 Luciferase reporter assay, qRT-PCR, Western blot 22540680
27 MMP14 miR-145 Reporter assay, Microarray 21351259
31 STAT3 miR-21 Western blot, Other 20048743
31 STAT3 miR-20b qRT-PCR, ELISA, ChIP, Western blot 20232316
31 EPB41L3 miR-223 Luciferase reporter assay, Western blot 21628394
31 TNFSF10 miR-222 Western blot 18246122
32 TOB1 miR-218 Luciferase reporter assay 23060446
33 CCNA2 let-7b Immunoblot, Immunofluorescence, Luciferase reporter assay, qRT-PCR 18379589