Table 2. PAS Domain Boundaries in Representative Clock Proteins.
proteina | domainb | residues | motifc | residues |
---|---|---|---|---|
CLOCK | PAS-A | 106–258 | PAS 1 | 107–177 |
PAS-B | 274–376 | PAS 2 | 262–332 | |
PAC | 336–379 | |||
BMAL1 | PAS-A | 142–320 | PAS 1 | 143–215 |
PAS-B | 353–442 | PAS 2 | 327–397 | |
PAC | 402–445 | |||
PER2 | PAS-A | 191–315 | PAS 1 | 179–246 |
PAS-B | 329–435 | PAS 2 | 319–385 | |
PAC | 393–436 |
Determined from domain boundaries in crystal structures 4F3L and 3GDI; includes A′α helix (PAS-A) or Jα helix (PAS-B) where appropriate.
From the UniPROT database (http://www.uniprot.org).