Table 4. Markers of renal dysfunction associated with Schistosoma infection by univariable logistic regression.
| Schistosoma +ve | Schistosoma—ve | Odds ratio (95%CI) | p-value | |
|---|---|---|---|---|
| (n = 84) | (n = 160) | |||
| Number (%) or Median [IQR] | Number (%) or Median [IQR] | |||
| Renal dysfunction* | 51 (60.7) | 61 (38.1) | 2.51 (1.46–4.31) | 0.001 |
| eGFR † (ml/min/1.73m2) | 102.7 [77.5–131.7] | 115.4 [92.9–141.8] | 3.6 | 0.059 |
| eGFR <60ml/min/1.73m2 | 6 (7.2) | 9 (5.6) | 2.61 (1.35–5.04) | 0.014 |
| Albuminuria | 47 (55.9) | 55 (34.4) | 2.92 (1.61–5.27) | 0.001 |
| Hematuria | 14 (16.7) | 11 (6.9) | 2.71 (1.17–6.27) | 0.02 |
| Pyuria | 8 (4.9) | 6 (7.1) | 2.70 (0.91–8.06) | 0.07 |
*the primary study outcome (defined operationally as eGFR <60mL/min/1.73m2 and/or albuminuria >20mg/L in a single urine test)
†eGFR = estimated glomerular filtration rate as calculated by modified Schwartz equation