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. 2014 Dec 8;28(1):38–42. doi: 10.1021/tx500444e

Figure 3.

Figure 3

(A) Human oxidoreductases participating in the metabolism of drugs (calculation for drugs under development and marketed drugs). n = 4192 reactions; 860 drugs used in calculations. (B) Human P450 enzymes in the metabolism of drugs (data calculated for minor and major reactions, drugs under development, and marketed drugs). n = 4058 reactions; 860 drugs used in calculations.