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. 2015 Jan 17;10:665–675. doi: 10.2147/IJN.S76307

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© 2015 Situ et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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In vitro antitumor activity results of blank and DOX-loaded micelles.

Notes: In vitro cytotoxicity of blank (A) and DOX-loaded micelles (B) against BEL-7402 cells. (C) BEL-7402 cells treated with DOX HCl, Dex-PLGA micelles, and A54-Dex-PLGA micelles. Cells were stained with calcein acetoxymethyl ester (green) for visualization of live cells.

Abbreviations: A54-Dex-PLGA/DOX, doxorubicin-loaded A54 peptide-functionalized poly(lactic-co-glycolic acid)-grafted dextran; DOX HCI, doxorubicin hydrochloride.