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. 2015 Jan 17;10:665–675. doi: 10.2147/IJN.S76307

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© 2015 Situ et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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In vivo targeting imaging of A54-Dex-PLGA micelles.

Notes: Fluorescence images (A) of the mice bearing BEL-7402 and HepG2 cells on left and right sides at different time points after subcutaneous injection of ICG-loaded A54-Dex-PLGA micelles. (B) Ex vivo fluorescence images of dissected organs and tumors at 48 hours postinjection. (C) The accumulation of ICG/A54-Dex-PLGA micelles in tissues was calculated as %ID/g (the percentage of the fluorescent intensity per gram of tissue).

Abbreviations: ICG, indocyanine green; A54-Dex-PLGA, A54 peptide-functionalized poly(lactic-co-glycolic acid)-grafted dextran.