Table 1.

A table summarizing the clinical characteristics of patients from which these new cell lines were derived and established

Cell lines	FA34	FA44	FA49	FA98	PME1
Sex/age (years)	Female/34	Male/58	Male/53	Male/80	Male/73
Smoking habits	Lifetime nonsmoker	Chronic smoker	Chronic smoker	Chronic smoker	Ex-smoker
Tissue origin	Pleural fluid	Pleural fluid	Pleural fluid	Pleural fluid	Pleural fluid
Tumor cell type	Adenocarcinoma	Adenocarcinoma	Adenocarcinoma	Adenocarcinoma	Malignant pleural mesothelioma
Staging	IV	IV	IV	IV	IV
Prior treatment	Paclitaxel, pemetrexed, cisplatinum, erlotinib	Paclitaxel, carboplatin	Paclitaxel, carboplatin	Empirical erlotinib	No treatment prior to collection of biopsy specimen
Tumorigenicity in nude mice	Yes	Yes	Yes	Yes	No
Potential oncogenic mutations	EML4-ALK translocation variant 2	KRAS mutation at codon 12 (G215T)	KRAS mutation at codon 12 (G219A)	EGFR and KRAS wild type