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. Author manuscript; available in PMC: 2016 Jan 1.
Published in final edited form as: Circ Heart Fail. 2014 Dec 5;8(1):109–118. doi: 10.1161/CIRCHEARTFAILURE.114.001297

Figure 2.

Figure 2

Functional assessment of cardiomyocyte p65 NF-κB deletion with pressure-overload. TAC was performed on sham, WT, and KO mice and followed for 6 weeks. (A) Characteristic M-mode transthoracic echocardiography at mid-papillary level. (B) Graphical representation of ejection fraction, heart weight/body mass ratio (×10−3), and wet/dry lung mass in respective animals. (C) Real-time PCR for hypertrophic markers (β-MHC - β-myosin heavy chain; Acta - smooth muscle α-actinin; ANP - atrial natriuretic peptide; BNP - brain natriuretic peptide). (p<0.05, *vs. WT sham, †vs. KO sham, ‡vs. WT post-TAC).