Table 1.

Bleeding Outcomes by Tertile of Hospital-level Unadjusted Bleeding Rates

Variable	Low (n=430 sites)	Average (n=431 sites)	High (n=431 sites)	p-value
Median overall unadjusted bleeding rate (IQR), %	3.5 (2.9, 3.9)	5.2 (4.8, 5.7)	7.7 (6.9, 9.1)	<0.01
Bleeding components
Median bleeding event within 72 hours (IQR), %*	0.9 (0.6, 1.3)	1.6 (1.1, 2.1)	2.4 (1.6, 3.4)	<0.01
Median bleeding at access site (IQR), %	0.2 (0.1, 0.4)	0.4 (0.2, 0.7)	0.5 (0.2, 1.1)	<0.01
Median access site hematoma (IQR), %	0.4 (0.2, 0.6)	0.6 (0.4, 1.0)	0.9 (0.6, 1.5)	<0.01
Median retroperitoneal bleed (IQR), %	0.1 (0.0, 0.2)	0.2 (0.1, 0.3)	0.2 (0.1, 0.4)	<0.01
Median gastrointestinal bleed (IQR), %	0.1 (0.0, 0.3)	0.3 (0.1, 0.4)	0.4 (0.2, 0.6)	<0.01
Median genitourinary bleed (IQR), %	0.0 (0.0, 0.0)	0.0 (0.0, 0.1)	0.1 (0.0, 0.2)	<0.01
Median other/unknown site bleed (IQR), %	0.1 (0.0, 0.2)	0.2 (0.1, 0.4)	0.3 (0.1, 0.6)	<0.01
Median pericardial tamponade (IQR), %	0.0 (0.0, 0.1)	0.0 (0.0, 0.1)	0.0 (0.0, 0.1)	<0.01
Median hemorrhagic stroke (IQR), %	0.0 (0.0, 0.0)	0.0 (0.0, 0.0)	0.0 (0.0, 0.1)	0.20
Median transfusion with pre-PCI hemoglobin >8 g/dl and no CABG during index hospitalization (IQR), %	0.5 (0.1, 0.9)	1.0 (0.6, 1.5)	1.8 (1.2, 2.5)	<0.01
Median hemoglobin decrease ≥3 g/dl with pre-hemoglobin ≤16 g/dl (IQR), %	1.4 (1.0, 1.9)	2.2 (1.7, 2.8)	3.4 (2.5, 4.5)	<0.01
Median pre-transfusion hemoglobin among transfused patients (IQR), %	11.3 (10.8, 11.8)	11.2 (10.8, 11.6)	11.3 (10.9, 11.7)	0.20

^*Includes arterial access site, retroperitoneal, gastrointestinal, or genitourinary bleeding

IQR indicates interquartile range