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. Author manuscript; available in PMC: 2015 Jul 22.
Published in final edited form as: Oncogene. 2014 Jan 27;34(4):516–524. doi: 10.1038/onc.2013.585

Figure 3. Lack of immune cell infiltration in αv−/p53− SCCs.

Figure 3

Immunohistochemical analysis and quantification of the staining for CD45 (a,b), CD3 (c,d), Gr-1 (e,f), F4/80 (g,h), and Nk1.1 (i,j) in histologic sections from αv+/p53−, αv−/p53+, and αv−/p53− SCCs. Note that sections from the same tumors are shown in e and g for αv+/p53− and αv−/p53+ tumors to illustrate the inverse correlation frequently observed between Gr-1 and F4/80 staining. Quantification of the staining in αv+/p53− SCCs (1, blue columns), αv−/p53+ (2, red columns) and αv−/p53− SCCs (3, green columns) is represented as the average number of cells per field in 5 tumors per genotype. *p< 0.05 for comparisons with each of the other two groups.