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. 2014 Aug 15;9(2):461–471. doi: 10.1038/ismej.2014.142

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Copyright © 2015 International Society for Microbial Ecology

This work is licensed under a Creative Commons Attribution 3.0 Unported License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/3.0/

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Survey of cobalamin synthesis genes across aquatic metagenomes. (a) The full set of cob/cbi genes and subset of eleven representative marker genes (black) used in the screen and their abundance (total number of detected genes). (b) Taxonomic breakdown of all detected cob/cbi genes across 430 aquatic metagenomes. (c) Distributions of thaumarchaeotal, cyanobacterial and proteobacterial cobalamin gene contributions (% of total cob/cbi genes) for 28 different studies. (d) Clustering and heatmap visualization of taxonomic composition of cob/cbi genes for the 430 metagenomes. The color scale reflects the proportion of cob/cbi genes in each sample affiliated with a particular taxonomic group. More information on each sample can be found in Supplementary Table S1. (e) Global distribution of cobalamin synthesis genes. To emphasize Thaumarchaeota-rich metagenomes, data points with higher thaumarchaeotal contributions have been slightly enlarged and overlayed preferentially in cases where there are overlapping data points. The Thaumarchaeota-rich Arctic metagenome described in the text is indicated by an asterisk.