TABLE 2.

IC₅₀ values for the inhibition of PKC isozymes by inhibitors

	Staua	Bisb	1NA-PP1	1NM-PP1	2NM-PP1
	nm	nm	nm	nm	nm
WT PKCδ	41.2 ± 1.6	32.4 ± 3.0	>100,000	>100,000	>1,000,000
AS PKCδ	1671.0 ± 45.5	221.1 ± 31.9	154.0 ± 14.3	2,598.7 ± 162.8	>100,000
WT PKCϵ	1.5 ± 0.1	6.2 ± 1.1	>100,000
WT PKCγ	18.1 ± 1.5	30.0 ± 2.2	>100,000

^a Stau, staurosporine.

^b Bis, bisindolylmaleimide I.