TABLE 1.

Sequences of primers, siRNA sequences, and shRNA sequences used in real time PCR experiments

Name	Sequence
Primers
mPGRN	Forward 5′-TTC ACA CAC GAT GCG TTT CA-3′
	Reverse 5′-AGG GCA CAC AGA AAA AG-3′
mPIRO	Forward 5′-CCT TTT TCA GTT TTC CTC GCC-3′
	Reverse 5′-TGC ACA CTG AAG GAC CTG GAA-3′
mc-Fos	Forward 5′-GGT GAA GAC CGT GTC AGG AG-3′
	Reverse 5′-TAT TCC GTT CCC TTC GGA TT-3′
mNFATc1	Forward 5′-GAG TAC ACC TTC CAG CAC CTT-3′
	Reverse 5′-TAT GAT GTC GGG GAA AGA GA-3′
mTRAP	Forward 5′-TCA TGG GTG GTG CTG CT-3′
	Reverse 5′-GCC CAC AGC CAC AAA TCT-3′
mOSCAR	Forward 5′-GGA ATG GTC CTC ATC TGC TT-3′
	Reverse 5′-GGA ATG GTC CTC ATC TGC TT-3′
mGAPDH	Forward 5′-TCA AGA AGG TGG TGA AGC AG-3′
	Reverse 5′-AGT GGG AGT TGC TGT TGA AGT-3′
hPGRN	Forward 5′-TCC CCC TAA CCA AAT TCT CC-3′
	Reverse 5′-GGG ATG GCA GCT TGT AAT GT-3′
hPIRO	Forward 5′-CCT TTT TCA GTT TTC CTC GCC-3′
	Reverse 5′-TGC ACA CTG AAG GAC CTG GAA-3′
hGAPDH	Forward 5′-TCA AGA AGG TGG TGA AGC AG-3′
	Reverse 5′-GGT GGA GGA GTG GGT GTC-3′
siRNA sequences (duplex)
mPIRO-siRNA 1	Sense 5′-CUC CAU AUU CCA GGU CCU U(dTdT)-3′
	Antisense 5′-AAG GAC CUG GAA UAU GGA G(dTdT)-3′
mPIRO-siRNA 2	Sense siRNA 2 5′-CGU CCU AAA GUG UGU AUU U(dTdT)-3′
	Antisense siRNA 2 5′-AAA UAC ACA CUU UAG GAC G(dTdT)-3′
mPIRO-siRNA 3	Sense siRNA 3 5′-CGU CCU AAA GUG UGU AUU U(dTdT)-3′
	Antisense siRNA 3 5′-AAA UAC ACA CUU UAG GAC G(dTdT)-3′
hPIRO-siRNA1	Sense siRNA 3 5′-CAC UUA UGA GUG AGA ACA U(dTdT)-3′
	Antisense siRNA 3 5′-AUG UUC UCA CUC AUA AGU G(dTdT)-3′
hPIRO-siRNA2	Sense siRNA 3 5′-CUC CAU UUU UCA AGU CUC A(dTdT)-3′
	Antisense siRNA 3 5′-UGA GAC UUG AAA AAU GAC G(dTdT)-3′
hPIRO-siRNA3	Sense siRNA 3 5′-CUG UCU UCU UGC CAU AUU U(dTdT)-3′
	Antisense siRNA 3 5′-AAA UAU GGC AAG ACA G(dTdT)-3′
shRNA sequences (vector: pMLP-GFP)
mPGRN-shRNA 1	5′-AAAGGAGGTGAAGTGCGACATATAGTGAAGCCACAGATGTATATGTCGCACTTCACCTCCTTC-3′
mPGRN-shRNA 2	5′-ATGACCTGATCCAGAGTAAGTATAGTGAAGCCACAGATGTATACTTACTCTGGATCAGGTCAC-3′
mPGRN-shRNA 3	5′-AGAGAAGGGCATTTCTGCCATATAGTGAAGCCACAGATGTATATGGCAGAAATGCCCTTCTCC-3′
hPGRN-shRNA 1	5′-ATGCCCTGATGGTTCTACCTGATAGTGAAGCCACAGATGTATCAGGTAGAACCATCAGGGCAC-3′
hPGRN-shRNA 2	5′-AAAGGACACTTCTGCCATGATATAGTGAAGCCACAGATGTATATCATGGCAGAAGTGTCCTTC-3′
hPGRN-shRNA 3	5′-ACAACGTGAAGGCTCGATCCTATAGTGAAGCCACAGATGTATAGGATCGAGCCTTCACGTTGC-3′
hPGRN-shRNA 4	5′-ACCCAGGGCTACACGTGTGTAATAGTGAAGCCACAGATGTATTACACACGTGTAGCCCTGGGG-3′