. 2014 Dec 5;290(4):2244–2250. doi: 10.1074/jbc.M114.600718

TABLE 3.

Formate production by liver mitochondria from folate-replete and folate-deficient rats

Rate of formate production from different precursors (nmol/mg of protein/10 min) by isolated rat liver mitochondria from animals fed either a folate-replete or folate-deficient diet. Values are given as the mean (S.D.), n = 5, in each group.

Substrate	Folate-replete	Folate-deficient
Serine (1 mm)	6.81 ± 1.24	1.03 ± 0.64^a
Glycine (3 mm)	0.96 ± 0.69	0.64 ± 0.76
Dimethylglycine (1 mm)	1.11 ± 0.75	3.98 ± 2.83^a
Sarcosine (1 mm)	1.03 ± 0.77	4.57 ± 2.55^a

^a A significant difference (p < 0.05) from the folate-replete value.