Table 2.

Parameters of the P100 component of visual evoked potentials in the controls, whole MS group and subgroups of MS patients: non-fatigued (I), moderately (II) and severely (III) fatigued

	Controls (n = 40)	MS patients (n = 86)		MS subgroup I (n = 29)		MS subgroup II (n = 31)		MS subgroup III (n = 26)
L: P100 latency (ms)
Mean	101.8	117.3	p (MS-contr) = 0.00001	113.9	p (I-contr) = 0.00001	118.3	p (II-contr) = 0.00001	119.8	p (III-contr) = 0.00001
SD	5.0	21.6		14.9		16.1	p (I–II) = 0.28	31.9	p (I–III) = 0.38
									p (II–III) = 0.82
R: P100 latency (ms)
Mean	102.2	119.9	p (MS-contr) = 0.00001	113.8	p (I-contr) = 0.00001	121.1	p (II-contr) = 0.00001	125.1	p (III-contr) = 0.00001
SD	4.7	15.8		12.9		14.6	p (I–II) = 0.02	18.4	p (I–III) = 0.006
									p (II–III) = 0.2
Relative P100 latency:
Mean	2.14	9.95	p (MS-contr) = 0.00001	6.49	p (I-contr) = 0.0002	12.15	p (II-contr) = 0.00001	11.16	p (III-contr) = 0.00001
SD	1.96	11.13		6.63		13.13	p (I–II) = 0.15	11.96	p (I–III) = 0.038
									p (II–III) = 0.89
L: P100 amplitude (µV)
Mean	11.4	9.39	p (MS-contr) = 0.027	9.72	p (I-contr) = 0.15	9.34	p (II-contr) = 0.057	9.06	p (III-contr) = 0.052
Median	4.5	4.92		5.25		4.63	p (I–II) = 0.49	5.08	p (I–III) = 0.65
SD									p (II–III) = 0.83
R: P100 amplitude (µV)
Mean	10.6	8.97	p (MS-contr) = 0.075	8.96	p (I-contr) = 0.15	9.25	p (II-contr) = 0.22	8.63	p (III-contr) = 0.097
SD	4.4	5.05		8.43		7.92	p (I–II) = 0.83	5.12	p (I–III) = 0.012
				5.07		5.13			p (II–III) = 0.65
Relative P100 amplitude:
Mean	0.97	1.02	p (MS-contr) = 0.47	1.07	p (I-contr) = 0.55	1.02	p (II-contr) = 0.46	0.98	p (III-contr) = 0.68
SD	0.22	0.4		0.56		0.28	p (I–II) = 0.53	0.38	p (I–III) = 0.50
									p (II–III) = 0.36

Bold values are statistically significant at (p < 0.05)

L left eye, R right eye)