Table 1.
Firing properties of V1 neurons
% Visually responsive neurons | Evoked response index |
Orientation selectivity index |
Normalized spontaneous firing rate |
||||
---|---|---|---|---|---|---|---|
Left eye | Right eye | Left eye | Right eye | Left eye | Right eye | ||
Vehicle | 99.05±1.9 | 0.73±0.046 | 0.62±0.18 | 0.75±0.10 | 0.69±0.12 | 0.65±0.17 | 0.59±0.30 |
U0126 | 99.80±0.52 | 0.71±0.12 | 0.67±0.06 | 0.72±0.05 | 0.67±0.06 | 0.57±0.17 | 0.61±0.17 |
CGP57380 | 99.26±1.2 | 0.78±0.09 | 0.71±0.14 | 0.72±0.07 | 0.75±0.05 | 0.51±0.24 | 0.52±0.27 |
Firing properties of V1 neurons were unaffected by U0126 and CGP57380. Average (±SD) firing properties of units recorded near to the site of drug infusion are shown. No significant differences were observed across drug treatments for any property. ERI, OSI, spontaneous firing rate: 1-way ANOVA P > 0.25; % visually responsive neurons: ANOVA on ranks P > 0.6; vehicle n = 7 hemispheres, U0126 n = 7, CGP57380 n = 6.