Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Dec 18;1(12):866–881. doi: 10.18632/oncoscience.110

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © 2014 Ryu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

PMC Copyright notice

Two apoptosis assays—Annexin V-FITC and caspase 3/7—were performed to analyze the effect of cordycepin on apoptosis in SNU719 cells. (A) The Annexin V-FITC apoptosis detection assay was performed in triple repeats. Early apoptosis was suppressed by cordycepin by up to 64%, but increased late apoptosis/necrosis by up to 31% in SNU719 cells treated with cordycepin for 48 h. SDW, blank treatment; Cordycepin, 125 μM cordycepin treatment. (B) The caspase 3/7 assay was conducted in triple repeats. Caspase 3 and 7 activities were gradually decreased in SNU719 cells in response to 100 and 200 μM cordycepin treatments. Numbers 0, 100, and 200 indicate the micromolar concentrations of the cordycepin treatments. P-values <0.05 (95% confidence) were considered statistically significant.