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. 2015 Feb;159:127–137. doi: 10.1016/j.aquatox.2014.12.007

Fig. 4.

Fig. 4

The pH-dependent uptake of propranolol. Shown are the apparent permeability coefficients (Papp) for uptake (PappA:B, white bars) and efflux (PappB:A, gray bars) of propranolol (1 μg L−1) across the DSI gill cell epithelium at 6 h in asymmetrical conditions at three different pHs. Significant differences between uptake Papp or efflux Papp are indicated by asterisk (one-way ANOVA; ***P < 0.001). All experiments were performed in triplicate or more (n = 3–5) from two biological replicates and values are shown as means ± SEM.