Skip to main content
. 2014 Sep 17;29(1):30–39. doi: 10.1002/ptr.5218

Figure 3.

Figure 3

Effects of BHH10 on BMD and bone morphometric analysis of the whole femur (A) and femoral neck (B) in ovariectomized (OVX) rats. BHH10 altered the trabecular bone volume (BV/TV), connectivity density (Conn. D), trabecular number (Tb. N), trabecular thickness (Tb. Th), and trabecular separation (Tb. Sp) of the trabecular bone at the total femur (250, 500 mg/kg) and neck femur (250 mg/kg). 3D trabecular images of a vertical section of proximal femur (C) and femoral neck (D) in SHAM, OVX, alendronate (ALN), 17β-estradiol (E2), and 250 mg/kg BHH10 in rats. The trabecular bone loss was significantly higher in the OVX group than in the SHAM group. The trabecular bone volume was higher in the ALN, E2, and 250 mg/kg BHH10 groups than in the OVX group. The data are expressed as the mean ± S.E.M. #p < 0.05, ##p < 0.01, and ###p < 0.001 compared with SHAM. *p < 0.05, **p < 0.01, and ***p < 0.001 compared with OVX. ap < 0.01 compared with ALN. bp < 0.01 compared with E2.