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. 2014 Sep 17;29(1):30–39. doi: 10.1002/ptr.5218

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Copyright © 2014 John Wiley & Sons, Ltd.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effects of BHH10 on bone metabolic markers in the serum of ovariectomized (OVX) rats. The levels of serum alkaline phosphatase (ALP) (A), osteocalcin (OCN) (B), C-telopeptide type 1 collagen (CTX) (C), and bone morphogenetic protein-2 (BMP-2) (D) were determined using colorimetric methods or enzyme-linked immunosorbent assay in SHAM control rats, OVX rats, alendronate (ALN)-treated, 17β-estradiol (E2)-treated, or BHH10-treated rats. The data are expressed as the mean ± S.E.M. ^#p < 0.001 compared with SHAM. *p < 0.05 and ***p < 0.001 compared with OVX, ^ap < 0.01 compared with ALN. ^bp < 0.01 compared with ALN.