TABLE 1.

Metabolic parameters of 16-week-old male PPARγ2 knockout and wild-type mice

	Normal diet		12 weeks on HFD
	Wild type	Knockout	Wild type	Knockout
Glucose (mg/dl)	130 ± 9.0	147 ± 5.9	236 ± 15.5	238 ± 11.1
Glucose fasting (mg/dl)	63 ± 4.1	88 ± 5.1†	106.9 ± 12.8	113.0 ± 14.9
Triglycerides (mmol/l)	0.93 ± 0.12	0.87 ± 0.15	0.68 ± 0.17	0.78 ± 0.09
Free fatty acids (μmol/l)	295 ± 63	231 ± 17	250 ± 32	219 ± 22
Insulin (μg/l)	0.49 ± 0.10	0.34 ± 0.05	0.98 ± 0.20	1.31 ± 0.13
Insulin fasting (μg/l)	0.14 ± 0.03	0.35 ± 0.11
Leptin (ng/ml)	2.77 ± 0.44	4.13 ± 0.56*	8.76 ± 1.13	16.66 ± 3.31*
Adiponectin (μg/ml)	15.2 ± 1.2	7.9 ± 1.2‡	11.3 ± 1.09	7.46 ± 1.63*

Data are means ± SE. n = 5/10 for 16-week-old mice fed normal diet and HFD.

^*P < 0.05

^†P < 0.01

^‡P < 0.001.