TABLE 2.

SNPs in the SCARB1 region associated with serum lycopene in transethnic fixed-effects meta-analysis¹

		Meta-analysis				African American				Hispanic American				European American
SNP	A1/A2	P	β	P-het	I2	P	β	CAF	MAF	P	β	CAF	MAF	P	β	CAF	MAF
rs1672879*	G/T	2.68 × 10−9	−0.14	0.25	28.3	7.85 × 10−5	−0.12	0.59	0.41	6.26 × 10−6	−0.20	0.77	0.23	0.14	−0.09	0.97	0.03
rs701107	A/G	2.43 × 10−8	−0.13	0.30	17.2	2.59 × 10−4	−0.12	0.60	0.40	2.04 × 10−5	−0.19	0.77	0.23	0.15	−0.09	0.97	0.03
rs838861	T/C	2.32 × 10−8	−0.14	0.19	40.4	7.29 × 10−4	−0.11	0.67	0.33	4.65 × 10−6	−0.20	0.78	0.22	0.14	−0.09	0.97	0.03

¹Baseline model was further adjusted for age, BMI, and first 4 principal components of ancestry. *SNP with the most significant association in the meta-analysis with serum lycopene for this region. A1/A2, coded/noncoded allele; CAF, coded allele (A1) frequency; I², index of the degree of heterogeneity; MAF, minor allele frequency; P-het, P values for heterogeneity, indicating whether effect sizes are homogeneous across ancestry samples; SCARB1, scavenger receptor class B member 1; SNP, single nucleotide polymorphism.