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. 2015 Jan 17;13:3. doi: 10.1186/s12951-014-0063-3

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© Zhang et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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The top 10 genes with the highest expression changes in the two cell types after treatment with FeNPs. A and B: Induced genes in the THP-1 cells. C and D: Induced genes in the HepG2 cells. E and F: Repressed genes in the THP-1 cells. G and H: Repressed genes in the HepG2 cells. 50-up and 100-up: induced genes in cells treated with 50 μg/mL and 100 μg/mL of FeNPs, respectively; 50-down and 100-down: repressed genes in cells treated with 50 μg/mL and 100 μg/mL of FeNPs, respectively. Some uncharacterized genes with fold changes greater than the lowest fold changes in these plots are not shown in this figure.