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. 2015 Jan 17;13:3. doi: 10.1186/s12951-014-0063-3

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© Zhang et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Cluster analysis of genes. Fifty-five FeRGs from the two cell lines were clustered according to their expression levels using a hierarchical clustering. The heatmap was drawn with Java TreeView. Red and green represent up- and down-regulation, respectively. The color depth reflects the expression level between −3 and +3 (marker). The numbers of genes in Clusters A to D are shown in parentheses. The fold changes of 10 representative genes in four clusters are shown in the zoomed images. T-50, H-50, T-100, and H-100, see Figure 4.