Skip to main content
. Author manuscript; available in PMC: 2015 Jan 23.
Published in final edited form as: Pediatr Blood Cancer. 2010 Dec 27;57(3):443–453. doi: 10.1002/pbc.22921

Fig. 1.

Fig. 1

PR-104 in vitro activity. A: Relative sensitivity of the cell lines using the IC50 values displayed by histotype. The black line indicates the median IC50 (16.5 μM) for the panel. Cells were exposed to PR-104 for 96 hr under aerobic conditions at concentrations from 10 nM to 100 μM, and viable cells determined by fluorescein diacetate staining. Concentrations of PR-104 that inhibited cell proliferation by 50% (IC50) are plotted for each cell line of each histotype. B: Typical growth inhibition curves for Rh30 and COG-LL-317. Error bars represent standard deviations for each concentration tested.