Figure 3.

Periostin is important for the induction of inflammation in BLM-challenged mice. BLM or saline was administered intratracheally into wild-type or periostin-deficient mice (BALB/c background) on Day 0. Bronchoalveolar lavage fluid (BALF) and the lung tissue were prepared on Day 7. The numbers of total cells, neutrophils, macrophages, lymphocytes, and eosinophils in BALF from saline-administered (n = 8) or BLM-administered wild-type mice (n = 16) or BLM-administered periostin-deficient mice (n = 8) are shown.