TABLE 1.

CHARACTERISTICS OF PATIENTS WITH CHEMOTHERAPEUTIC AGENT–INDUCED ILD

				Histology
Patient Number	Age (Years)	Gender	Sample	Carcinoma	ILD	Thoracic Irradiation	Total Dose	Length of Administration	Smoking Status
Bleomycin-induced
1	56	Male	Autopsy	Squamous (lung)	DAD (organizing/fibrotic)	Unknown	Unknown	Unknown	Unknown
2	66	Male	Autopsy	Squamous (mandible)	DAD (organizing/fibrotic)	12,000 rad	190 mg	28 days	Unknown
3	67	Female	Autopsy	Squamous (genitalia)	DAD (organizing/fibrotic + squamous metaplasia)	4,000 rad	300 mg	70 days	Unknown
4	56	Male	Autopsy	Squamous (hypopharynx)	DAD (organizing/fibrotic + squamous metaplasia)	3,600 rad	195 mg	91 days	Unknown
5	69	Male	Autopsy	Squamous (skin)	DAD (exudative/organizing + acute pulmonary edema)	6,000 rad	300 mg	140 days	Unknown
Gefitinib-induced
1	69	Female	Biopsy	Adeno	DAD (fibrotic + microscopic honeycombing)		3.75 g	15 days	Nonsmoker
2	66	Female	Biopsy	Adeno	Chronic interstitial fibrosis		7 g	28 days	Nonsmoker
3	62	Female	Biopsy	Adeno	DAD (fibrotic + microscopic honeycombing + squamous metaplasia)		13 g	52 days	Nonsmoker
4	62	Male	Biopsy	Adeno	DAD (fibrotic + microscopic honeycombing)		9.25 g	37 days	Nonsmoker
5	73	Male	Autopsy	Adeno	DAD (fibrotic + microscopic honeycombing + squamous metaplasia)		1.75 g	7 days	Smoker

Definition of abbreviations: DAD, diffuse alveolar damage; ILD, interstitial lung disease.