Predrug
evoked dopamine (DA) release is not correlated with the
app. Km for cocaine or amphetamine. (A)
Correlational analysis of the relationship between Vmax and predrug evoked dopamine release in the methylphenidate
(MPH; red; MPH, n = 11; DAT-tg, n = 10), amphetamine (AMPH, green; MPH, n = 9; DAT-tg, n = 9), and cocaine (COC, blue; MPH, n =
9; DAT-tg, n = 9) groups. (B) Predrug evoked dopamine
release did not correlate with cocaine or AMPH app. Km, but did correlate with app. Km of MPH. (C) Relationship between Vmax and predrug evoked dopamine release in DAT-tg mice. (D) Predrug
evoked dopamine release did not correlate with the app. Km of cocaine or AMPH, but did correlate with the app. Km of MPH.