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. 2015 Jan 17;9:575–601. doi: 10.2147/DDDT.S75221

Figure 6.

Figure 6

ALS regulates the expression and phosphorylation of PI3K, AMPK, p38 MAPK, Akt, mTOR, Erk1/2, PTEN, beclin 1, and LC3-I/II in PANC-1 and BxPC-3 cells.

Notes: Representative blots of phosphorylated PI3K, AMPK, p38 MAPK, Akt, mTOR, and Erk1/2 and total expression of PI3K, AMPK, p38 MAPK, Akt, mTOR, Erk1/2, PTEN, beclin 1, and LC3-I/II in PANC-1 and BxPC-3 cells.

Abbreviations: ALS, alisertib; PI3K, phosphatidylinositol 3-kinase; AMPK, 5′-AMP-dependent kinase; MAPK, mitogen-activated protein kinase; Akt, protein kinase B; mTOR, mammalian target of rapamycin; Erk, extracellular signal-regulated kinase; PTEN, phosphatase and tensin homolog; LC3, light chain 3.