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. 2015 Jan 17;9:537–560. doi: 10.2147/DDDT.S73689

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© 2015 Wang et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License

The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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PLB regulates EMT markers in BxPC-3 cells.

Notes: Cells were treated with 5 μM PLB for 24 hours and then protein samples were subject to Western blotting assay. Bar graphs showing the relative expression level of E-cadherin (A), N-cadherin (B), snail (C), slug (D), TCF-8/ZEB1 (E), vimentin (F), β-catenin (G), and ZO-1 (H) in BxPC-3 cells. Data represent the mean ± SD. *P<0.05, **P<0.01, and ***P<0.001 by one-way ANOVA.

Abbreviations: ANOVA, analysis of variance; Conc, concentration; EMT, epithelial to mesenchymal transition; PLB, plumbagin; SD, standard deviation; TCF-8/ZEB1, zinc finger E-box-binding homeobox 1; ZO-1, zona occludens protein 1.