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. 2014 Dec 19;9:32. doi: 10.1186/s13062-014-0032-7

Figure 5.

Figure 5

XIX th century doubts about the existence of membranes. A. In this vision, the cell is devoid of any membrane and all the properties of the cell are defined by the activity of the protoplasmic colloid. B. The cell is surrounded by an external layer (membrane) of which the nature is distinct to the rest of the protoplasm. Yet, in this view, the inside of the cell remains a colloid.