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. 2015 Jan 1;71(Pt 1):136–153. doi: 10.1107/S1399004714021683

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© Brown et al. 2015

This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.

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Box-and-whisker plots for refinement of EM structures at 4 Å resolution or better. (a) MolProbity clashscores before (pre) and after (post) restrained refinement with REFMAC. (b) Improvement in clashscores showing the mean of the differences and 95% confidence intervals. (c) FSC_average before and after restrained refinement. (d) Improvement in FSC_average showing the mean of the differences and 95% confidence intervals.