Table 2. Summary of sizes and dimensions of PDCs and micelles.
The volumes are calculated assuming that the PDCs and micelles are spherical and hydrated particles. Remarkable differences in the PDC loading could be observed under the simplified assumption that, for example, BR occupies 30.2nm3 per kDa. In contrast, FetA has a volume of only 2.99nm3 per kDa.
| Protein | Molecular weight (kDa) | Protein concentration (mgml1) | PDC R h (nm) | PDC spherical volume (nm3) | Micelles R h (nm) | Micelles spherical volume (nm3) | PDC nm3 per kDa |
|---|---|---|---|---|---|---|---|
| BR | 27 | 2.0 | 5.61 0.51 | 817.28 | 4.90 0.59 | 407.73 | 30.23 |
| Mbp-dHBx | 56 | 2.0 | 5.28 0.57 | 616.58 | 5.11 0.49 | 558.92 | 11.01 |
| FetA | 77 | 5.0 | 3.80 0.28 | 229.85 | 5.11 0.49 | 558.92 | 2.99 |