Table 4.
Iterative PLS-DA modeling cumulative results.
| Metabolite | HCC vs HCV | Cumulative PLS-DA | |||
|---|---|---|---|---|---|
| p-valuea | Sensitivity | Specificity | AUROCb | LVc | |
| Uric acid | 3.0E-03 | N/A | N/A | N/A | N/A |
| Xanthine | 5.2E-03 | N/A | N/A | N/A | N/A |
| Cholylglycine | 1.3E-02 | 0.95 | 0.62 | 0.89 | 3 |
| D-Leucic acid | 2.2E-02 | 0.95 | 0.62 | 0.89 | 3 |
| Glycolaldehyde, 3-Hydroxycapric acid | 2.3 E-02, 3.2E-02 | 0.92, 0.92 | 0.67, 0.62 | 0.92, 0.89 | 3,3 |
| Arachidonyl lysolecithin | 2.8E-06 | 0.89 | 0.91 | 0.91 | 3 |
| Dioleoylphosphatidylcholine | 1.0E-05 | 0.89, 0.92 | 0.95, 0.95 | 0.93, 0.93 | 3,4 |
p-value determined from the Welch’s t-test
area under the ROC curve
number of latent variables