Table 1. Detailed inventory of the 46 ABC transporter genes identified in the H. brasiliensis latex.
| ABC subfamily | Gene name | NCBI accession no. | Length (aa) | Topology | A. thaliana homolog | Common name | Identity (%) | |
|---|---|---|---|---|---|---|---|---|
| Subfamily A (ABCA*) | AOH; ABCA | HbABCA1 | KM035282 | 1883 | (TMD-NBD)2 | At2g41700 | AtABCA1 | 74 |
| ATH; ABCA | HbABCA2 | KM035283 | 970 | TMD-NBD | At3g47730 | AtABCA2 | 71 | |
| HbABCA7 | KM035284 | 939 | TMD-NBD | At3g47780 | AtABCA7 | 67 | ||
| Subfamily B (ABCB) | MDR; DPL(PGP) | HbABCB1 | KM035285 | 1363 | (TMD-NBD)2 | At2g36910 | AtABCB1 | 88 |
| HbABCB11 | KM035286 | 1283 | (TMD-NBD)2 | At1g02520 | AtABCB11 | 74 | ||
| HbABCB13 | KM035287 | 1135 | (TMD-NBD)2 | At1g27940 | AtABCB13 | 71 | ||
| HbABCB15 | HQ917533 | 1250 | (TMD-NBD)2 | At3g28345 | AtABCB15 | 77 | ||
| HbABCB19 | KM035288 | 1259 | (TMD-NBD)2 | At3g28860 | AtABCB19 | 89 | ||
| HbABCB20 | KM035289 | 1404 | (TMD-NBD)2 | At3g55320 | AtABCB20 | 86 | ||
| ATM; DPL(HMT) | HbABCB25 | KM035290 | 739 | TMD-NBD | At5g58270 | AtABCB25 | 83 | |
| TAP; DPL(TAP) | HbABCB26 | KM035291 | 702 | TMD-NBD | At1g70610 | AtABCB26 | 75 | |
| HbABCB28 | KM035292 | 660 | TMD-NBD | At4g25450 | AtABCB28 | 70 | ||
| DPL(LLP) | HbABCB29 | KM035293 | 650 | TMD-NBD | At5g03910 | AtABCB29 | 65 | |
| Subfamily C (ABCC) | MRP; OAD(MRP) | HbABCC2 | KM035294 | 1624 | (TMD-NBD)2 | At2g34660 | AtABCC2 | 79 |
| HbABCC5 | KM035295 | 1499 | (TMD-NBD)2 | At1g04120 | AtABCC5 | 81 | ||
| HbABCC13 | KM035296 | 1480 | (TMD-NBD)2 | At2g07680 | AtABCC13 | 66 | ||
| Subfamily D (ABCD) | PMP; FAE | HbABCD1 | KF701641 | 1337 | (TMD-NBD)2 | At4g39850 | AtABCD1 | 78 |
| HbABCD2 | KM035297 | 746 | TMD-NBD | At1g54350 | AtABCD2 | 69 | ||
| Subfamily E (ABCE) | RLI | HbABCE2 | KM035298 | 605 | NBD-NBD | At4g19210 | AtABCE2 | 93 |
| Subfamily F (ABCF) | GCN; ART(REG) | HbABCF1 | JX109943 | 605 | NBD-NBD | At5g60790 | AtABCF1 | 85 |
| HbABCF3 | KM035299 | 715 | NBD-NBD | At1g64550 | AtABCF3 | 82 | ||
| HbABCF4 | KM035300 | 726 | NBD-NBD | At3g54540 | AtABCF4 | 79 | ||
| HbABCF5 | KM035301 | 709 | NBD-NBD | At5g64840 | AtABCF5 | 79 | ||
| Subfamily G (ABCG) | WBC; EPD(WHITE) | HbABCG3 | KM035302 | 723 | NBD-TMD | At2g28070 | AtABCG3 | 81 |
| HbABCG5 | KM035303 | 626 | NBD-TMD | At2g13610 | AtABCG5 | 73 | ||
| HbABCG7 | KM035304 | 720 | NBD-TMD | At2g01320 | AtABCG7 | 78 | ||
| HbABCG11 | KM035305 | 649 | NBD-TMD | At1g17840 | AtABCG11 | 53 | ||
| HbABCG15 | KM035306 | 714 | NBD-TMD | At3g21090 | AtABCG15 | 68 | ||
| HbABCG20 | KM035307 | 715 | NBD-TMD | At3g53510 | AtABCG20 | 75 | ||
| HbABCG21 | KM035308 | 680 | NBD-TMD | At3g25620 | AtABCG21 | 68 | ||
| HbABCG22 | KM035309 | 738 | NBD-TMD | At5g06530 | AtABCG22 | 78 | ||
| HbABCG28 | KM035310 | 980 | NBD-TMD | At5g60740 | AtABCG28 | 68 | ||
| PDR; EPD(PDR) | HbABCG40 | KM035311 | 1438 | (NBD-TMD)2 | At1g15520 | AtABCG40 | 72 | |
| Subfamily I (ABCI) | NAP; CCM | HbABCI1 | KM035312 | 229 | NBD | At1g63270 | AtABCI1 | 86 |
| NAP; ISB | HbABCI6 | KM035313 | 335 | NBD | At3g10670 | AtABCI6 | 82 | |
| HbABCI7 | KM035314 | 492 | CYT | At1g32500 | AtABCI7 | 62 | ||
| HbABCI8 | KM035315 | 553 | CYT | At4g04770 | AtABCI8 | 81 | ||
| NAP; CBY(Y179) | HbABCI10 | KM035316 | 261 | NBD | At4g33460 | AtABCI10 | 71 | |
| HbABCI11 | KM035317 | 277 | NBD | At5g14100 | AtABCI11 | 72 | ||
| NAP; MKL; TGD | HbABCI13 | KM035318 | 343 | NBD | At1g65410 | AtABCI13 | 80 | |
| HbABCI14 | KM035319 | 325 | TMD | At1g19800 | AtABCI14 | 77 | ||
| HbABCI15 | KM035320 | 385 | SSA | At3g20320 | AtABCI15 | 73 | ||
| NAP; NO | HbABCI17 | KM035321 | 283 | NBD | At1g67940 | AtABCI17 | 73 | |
| HbABCI18 | KM035322 | 280 | NBD | At1g03900 | AtABCI18 | 76 | ||
| NAP; NO(ADT) | HbABCI19 | KM035323 | 300 | NBD | At1g03905 | AtABCI19 | 80 | |
| HbABCI20 | KM035324 | 329 | NBD | At5g02270 | AtABCI20 | 87 | ||
*ABCA: Similar to human abca1 protein; NBD: Nucleotide binding domain (ATP binding cassette domain); TMD: transmembrane domain; SSA: substrate binding protein; CYT: conserved soluble protein that interacts with ABC domain; DPL: Drug, peptide and lipid exporters; PGP: Similar to p-glycoprotein; LLP: Lipid A-like exporters, putative; OAD: Organic anion and drug exporters; HMT: Similar to yeast heavy metal transporters; TAP: Similar to the human transporters associated with antigen presentation; WHITE: Similar to Drosophila white protein; CCM: cytochrome C biogenesis family; ISB: iron sulfur center biogenesis family; CBY: family similar to putative cobalt uptake systems; Y179: similar to the M. janaschii Y179 protein subfamily; MKL: similar to the M. leprae MKL protein family; TGD: trigalactosyldiacyl glycerol: TGD1, 2 and 3 are components of a chloroplast phospholipid translocator; NO: proteins of unknown function, apparently unrelated to existing families and ADT: proteins of unknown function.