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. Author manuscript; available in PMC: 2016 Jan 31.
Published in final edited form as: Am J Transplant. 2015 Jan 12;15(2):333–345. doi: 10.1111/ajt.13014

Figure 2.

Figure 2

Male hearts transplanted to female RAG−/− recipients reconstituted with Marilyn CD4 T cells. At 2 weeks, allografts contained diffuse interstitial infiltrates of CD3 T cells (A) and Galectin-3+ macrophages (B) with limited periadventitial involvement of larger arteries. At 6 weeks, the interstitial infiltrates diminished, and large arteries developed adventitial and intimal infiltrates of CD3 T cells (C) and large numbers of macrophages (D). At 10 weeks, the arterial lesions contained decreased numbers of CD3 T cells (E), and increased macrophages (F). Original magnifications 200x (A-D) and 40x (E, F).