Table 3.
Log-adjusted parameter estimates and 95% confidence intervals of the association between baseline adiposity measures and baseline inflammation.
| Baseline body mass and adiposity measures | Log-Adjusted CRP (mg/L) | Log-Adjusted IL-6 (pg/mL) | ||||||
|---|---|---|---|---|---|---|---|---|
| Estimate | 95% CI | p-value | AIC* | Estimate | 95% CI | p-value | AIC* | |
| Total body mass (kg) | 0.02 | (0.01,0.03) | <0.01 | 496.0 | 0.01 | (0.01,0.02) | <0.01 | 303.5 |
| BMI (kg/m2) | 0.09 | (0.06,0.11) | <0.01 | 482.8 | 0.048 | (0.03,0.06) | <0.01 | 293.1 |
| Total body fat mass (kg) | 0.04 | (0.03,0.06) | <0.01 | 490.7 | 0.02 | (0.01,0.03) | <0.01 | 299.9 |
| Percent body fat (%) | 0.08 | (0.06,0.11) | <0.01 | 487.5 | 0.03 | (0.02,0.05) | <0.01 | 300.3 |
| Total abdominal fat volume (per 1000 cm3) | 0.12 | (0.04,0.20) | <0.01 | 504.6 | 0.08 | (0.04,0.13) | <0.01 | 311.5 |
| Abdominal visceral fat volume (per 1000 cm3) | 0.20 | (0.05,0.36) | 0.01 | 504.7 | 0.17 | (0.09,0.25) | <0.01 | 308.3 |
| Abdominal subcutaneous fat volume (per 1000 cm3) | 0.14 | (0.02,0.26) | 0.03 | 507.5 | 0.07 | (0.00,0.14) | 0.04 | 318.3 |
| Abdominal intermuscular fat volume (per 1000 cm3) | 0.85 | (−0.76,2.46) | 0.30 | 505.9 | 1.37 | (0.50,2.23) | <0.01 | 307.8 |
| Total thigh fat volume (per 1000 cm3) | 0.78 | (0.13,1.43) | 0.02 | 504.3 | 0.46 | (0.10,0.82) | 0.01 | 313.7 |
| Thigh intermuscular fat volume (per 1000 cm3) | 4.96 | (−3.85,13.76) | 0.27 | 502.0 | 9.60 | (4.95,14.25) | <0.01 | 295.5 |
| Thigh subcutaneous fat volume (per 1000 cm3) | 0.79 | (0.12,1.45) | 0.02 | 504.4 | 0.43 | (0.06,0.79) | 0.02 | 314.7 |
Models are adjusted for randomization group, race, gender and age. CT-derived measures of adiposity are expressed per 1000 cm3.
*
Akike’s Information Criteria (AIC) estimates are calculated among participants with baseline weight, BMI, DXA, and CT measures (n=162).